mucus membrane of human
stomach, near the
cardiac orifice. X 45.
c. Cardiac glands.
d. Their ducts.
cr. Gland similar to the intestinal glands, with goblet cells.
mm. Mucous membrane.
m. Muscularis mucosae.
m’. Muscular tissue within the mucous membrane.
|Transverse section of a
villus, from the human
intestine. X 350.
a. Basement membrane, here somewhat shrunken away from the epithelium.
c. Columnar epithelium.
d. Its striated border.
e. Goblet cells.
f. Leucocytes in epithelium.
f’. Leucocytes below epithelium.
h. Muscle cells cut across.
The majority of the cell's cytoplasm is occupied by mucinogen granules, except at the bottom. Rough endoplasmic reticulum, mitochondria, the nucleus, and other organelles are concentrated in the basal portion. The apical plasma membrane projects microvilli to increase surface area for secretion.
They are found scattered among the epithelial lining of many organs, especially the intestinal and respiratory tracts. In the respiratory tract, they are found inside the trachea, bronchus, and larger bronchioles.
In mucicarmine stains, goblet cells can be easily identified by the deep red mucin found within their cell bodies.
The term goblet refers to these cells' goblet-like shape. The apical portion is shaped like a cup, as it is distended by abundant mucinogen granules; its basal portion is shaped like a stem, as it is narrow for lack of these granules.
Other stimuli include viruses, bacteria, etc.
The content of this section is licensed under the GNU Free Documentation License (local copy). . It uses material from the Wikipedia article "Goblet cell" modified November 19, 2007 with previous authors listed in its history.